Inhalation aerosol technology allows rapid absorption into systemic circulation, delivering a more significant dose of Melatonin in a short amount of time. It's far more efficient than ingestion - a method of delivery that has random and sometimes poor bioavailability. In fact, ingested substances first pass through the metabolism and become less active than inhaled compounds that have direct access to the bloodstream without being metabolised first. Our products avoid first-pass metabolism and maximize bioavailablity, allowing for a lower, safer active ingredient concentration. According to a study from the Massachusetts Institute of Technology, the ideal nightly dosage of Melatonin is 0.3 milligrams. The research was conducted by Richard Wurtman, who pioneered the pharmaceutical use of melatonin as a sleep aid in 1994. Pills and supplements often sell 10 times that suggested amount in a single dose. This can lead to higher plasma melatonin levels the next day, which can cause a "hangover" effect that leaves users groggy.